2020年7月30日 · To distinguish monocyte-derived macrophages from their precursors, it is common to detect a set of cell surface markers along with their differential expression levels. Examples of antibodies for monocyte lineage markers: Ly6c1 antibodies, F4/80 antibodies, ITGAM/CD11b antibodies, CD68 antibodies, FCGR3A/CD16 antibodies, CD14 antibodies. Figure 1.

2023年12月26日 · 巨噬细胞（Macrophages，缩写为mø）是一种位于组织内的白血球，也称组织细胞（histocyte），源自单核细胞，由血液中的单核细胞穿过血管后分化而成。 单核细胞进入结缔组织后，体积增大，内质网和…

M0 macrophages highly express the macrophage-specific marker cluster of differentiation (CD)68 and lack pro-or anti-inflammatory activation protein markers [6, 7]. M1 macrophages, on...

We compared their activation states in M0 as reflected by markers or correlation factors expressed and secreted by the macrophages. Initially, we evaluated the expression of the surface markers MHC II and CD86 in the inflammatory microenvironment.

2023年3月30日 · In this work, we investigated macrophage autofluorescence as a distinct feature for classifying six different macrophage phenotypes, namely: M0, M1, M2a, M2b, M2c, and M2d. The identification...

2023年7月26日 · Apart from M0 and M2, we found inflammatory/activated macrophages in at least three different states: two transcriptionally different M1 populations (M1 ACOD1 and M1 CXCL5) and the IDA...

2023年3月2日 · Peripheral blood monocytes from healthy volunteers were differentiated into hMDM and polarized with either IFN-γ + LPS (M1) or IL-4 (M2). As expected, our M0, M1, and M2 hMDMs exhibited cell surface marker, phagocytosis, and gene expression profiles indicative of their different phenotypes.

2025年1月4日 · Functional experiments demonstrated that CXCL8 knockdown in M0 macrophages inhibited their proliferation, shifted polarization toward an M1-dominant phenotype, and reduced tumor-promoting M2...

2023年3月2日 · Peripheral blood monocytes from healthy volunteers were differentiated into hMDM and polarized with either IFN-γ + LPS (M1) or IL-4 (M2). As expected, our M0, M1, and M2 hMDMs exhibited cell surface marker, phagocytosis, and gene expression profiles indicative of their different phenotypes.

2022年7月19日 · Infiltration of M0 macrophages was significantly higher in HCC tissues than in normal liver tissues (P = 2.299e-07). Further analysis revealed 35 M0RGs that were associated with HCC prognosis; two M0RGs (OLA1 and ATIC) were constructed and validated as a prognostic signature for overall survival of patients with HCC.