2010年7月16日 · Based on this paper, the IC50 of sildenafil is 0.42 and the IC50 of icariin is 4.62 for PDE5 inhibition. Thus the dose of icarrin should be approximately ten times a given dose of sildenafil, thus approximately 250mg-1g for typical use.

2007年4月18日 · The prerequisites of a SARM (selective androgen reuptake modulator) are the ability of a compound to: "stimulate increases in strength and fat-free mass through testosterone mimetic properties, supporting bone growth, and maintaining and …

2011年3月23日 · Was thinking about this as a possibility, When using the PDE5 inhibitor Cialis 5mg every day as a maintenance to keep the PDE5 low does this cause any permanent enzyme changes? Such as does it after long continuous use cause the body to upregulate production of the enzyme or cause the body to...

2025年1月11日 · One key aspect of mangiferin is that it is thought to be a potent phosphodiesterase type 5 (PDE5) inhibitor, which can support cardiovascular health, pumps, blood flow, and erection quality. An extra added benefit of mangiferin is that it has been shown to improve blood flow to the skin, which may support skin health and appearance.

2013年7月20日 · Is ther much difference in the effectiveness of the liquid or tablet form of PDE5 inhibitor?Is one dropper from a 60ml bottle equivalent equal to 25mg of tablet form?

2017年8月7日 · Numerous preclinical studies have shown that PDE5 inhibitors can protect against pulmonary hypertension, endothelial dysfunction, myocardial ischemia/reperfusion injury, doxorubicin and post-myocardial infarction, heart failure, cardiac hypertrophy, heart transplantation, Duchenne muscular dystrophy and preconditioning of stem cells.

2015年4月15日 · I wanted to ask if there were any negative interactions between taking epi (current cycle) or other PH's in close proximity to a PDE5 inhibitor like V or C. I experimented with them as pwo and quite enjoy the pump from V but wanted to make sure they weren't potentially jeopardizing any...

2024年6月5日 · PDE5 inhibitor (Cialis 10Mg) induction of NO synthase (Thc 30mg Tincture+5mg Cbg) Hydration And Cell volumization (Creatine 5g+ 30G Glycerol+2G Taurine+1g Salt)

2022年9月2日 · It's not bunk. There's a large amount of ppl who do not respond to tadalifil or other pde5 inhibitor products like Viagra ect. Typically you can find 1 of the products in that category that works for you. But some ppl still don't respond to any of them and it's not uncommon. Products like these also don't just give you a hard on.

2023年8月25日 · Eurycomanone is the active compound found in the roots of Tongkat Ali/Eurycoma Longifolia that has been shown to increase the amount of total testosterone and free testosterone available in the bloodstream. At higher concentrations, Eurycomanone may also act as a phosphodiesterase type 5 (PDE5) inhibitor and support improved erection quality.