2 天之前 · Stains & molecular markers - PAX8; 1 of 9 members of paired box gene (PAX) family of transcription factors that regulate organogenesis

Board review style answer #2 D. PAX8+, CK7+, CK20-, ER / PR+, wild type p53, patchy / focal p16 Comment Here Reference: Endometrioid carcinoma Back to top Home > Uterus > Endometrioid carcinoma

Metanephric adenoma is a benign tumor composed of cytologically bland, embryonic looking epithelium with frequent psammomatous calcifications

2024年5月9日 · PAX8 expression can overlap between thyroid and parathyroid tumors and should not be considered as a reliable marker for differential diagnosis Differentiated high grade thyroid carcinoma:

2022年6月13日 · p40 is a truncated, nontransactivating p63 isoform that may stimulate cell proliferation, block apoptosis and favor unrestrained tumor growth

2020年1月30日 · PAX8: strong nuclear staining MLH1, MSH1, MSH2 and MSH6: typically retained but can show loss of at least one marker in 10% of cases (Int J Gynecol Pathol 2019;38 Suppl 1:S40)

2022年2月16日 · While the immunohistochemistry profile is not entirely concordant with a renal primary, especially with negative PAX8 and CAIX, the positivity of both CD10 and RCC Ma would suggest possibility of renal primary in the context of known history of renal cell carcinoma. Clinical and radiological correlation is recommended.

3 天之前 · Membranous staining Sensitive and specific for lung adenocarcinoma (positive) vs. mesothelioma (negative, Am J Surg Pathol 2001;25:43) May help distinguish, as part of a panel, hepatocellular carcinoma (usually negative) from metastatic adenocarcinoma to liver or cholangiocarcinoma (usually positive, Mod Pathol 2002;15:1279) Immunoexpression may …

2017年10月1日 · C. WT1+, PAX8+, calretinin-, BCL2+. As endosalpingiosis is composed of tubal type epithelium and thought to be derived from the Müllerian system, it is not surprising that this lesion is positive for PAX8 and WT1. Calretinin would be expected to stain lesions of mesothelial origin and ovarian theca origin.

Mesonephric adenocarcinoma is a rare, nonhuman papillomavirus (HPV) associated cervical neoplasm that is thought to derive from mesonephric / Wolffian remnants