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Molecular Cell aims to publish the best research in molecular biology. The journal covers core cellular processes. Molecular Cell is particularly interested in papers that answer longstanding questions, open new avenues of research, report unexpected findings, or change the way we think about biological processes. More
Issue: Molecular Cell
2025年1月2日 · In this issue of Molecular Cell, studies by Xu et al., Kimble et al. and Elango et al., examine how yeast and mammalian cells process DNA double-strand breaks that arise when the DNA replication machinery encounters a DNA nick.
New articles: Molecular Cell
1 天前 · By analyzing colorectal and tonsil cancer tissues, they uncover immune-modulating macrophage barriers and T cell adaptations in hypoxic regions. These findings provide critical insights into immune interactions and potential therapeutic targets, advancing precision oncology.
hnRNPM protects against the dsRNA-mediated interferon ... - Cell …
2024年5月29日 · Moreover, hnRNPM is essential for cell survival, 30, 31, 32 and its downregulation inhibits breast tumor metastasis. 33 Thus, we investigated hnRNPM binding by performing iCLIP analysis in human mammary epithelial (HMLE) cells.
Three-step mechanism of promoter escape by RNA polymerase II
2024年4月10日 · However, the exact molecular mechanism by which TFIIF is removed from RNA Pol II remains elusive. The mechanism of TFIIE and TFIIH release from RNA Pol II is also unclear.
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Molecular Cell aims to publish the best in molecular biology and beyond. In addition to fundamental cellular processes, we are interested in papers that show how molecular biology can be used to go beyond basic mechanisms to discover new biology, understand diseases, and to create new tools.
Spatiotemporal modeling of molecular holograms: Cell - Cell Press
2024年11月11日 · Spateo is a comprehensive framework for 3D reconstruction and characterization of spatial gradients and cellular interactions at whole-organ and embryo levels, using spatial transcriptomics. Importantly, Spateo also introduces morphometric vector field analyses that connect macroscopic cell morphogenesis with microscopic molecular dynamics.
Alphavirus infection triggers selective cytoplasmic ... - Cell Press
Mock or virus infected cells were harvested at times indicated in figure legends, and centrifuged for 5 min at 300xg at 4°C. Cell pellets were washed once with PBS and RNA extraction was done using RNeasy Plus kit (Qiagen #74136) according to the manufacturer instructions.
Issue: Molecular Cell
2024年12月19日 · In this issue of Molecular Cell, Sun et al. reveal that the long non-coding RNA (lncRNA) DNAJC3-AS1 plays a dual role in maintaining the rRNA processing function of fibrillarin (FBL) in cancer cells. It promotes FBL condensation while preventing abnormal aggregation, offering new therapeutic insights for cancer treatment by targeting lncRNAs ...
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Molecular Cell publishes 24 issues per year and releases new articles online each week. Our editorial team consists of PhD-trained editors who work closely with authors, reviewers, and the scientific editorial board to maintain the journal’s high standards and to bring exciting new discoveries to readers.