T lymphocytes in the intestinal mucosa: defense and tolerance
2019年2月20日 · In this review, we discuss the development and adaptation of T lymphocytes in the intestine, how these cells protect the host against pathogenic infections while tolerating …
Antigen-presenting cells as specialized drivers of intestinal T cell ...
2024年10月8日 · In this perspective, we describe our current understanding of how the T cell response is shaped by environment-associated antigens in the intestine and gaps in our …
Contemporary approach to the diagnosis and classification of …
2025年1月24日 · The broad category of intestinal T- and NK cell lymphomas and lymphoproliferative disorders encompasses a group of neoplastic T- and NK-cell lesions that …
Development and maintenance of intestinal regulatory T cells
2016年4月18日 · Understanding the development and the maintenance of intestinal T reg cells provides important insights into disease-relevant host–microorganism interactions. The …
Regulatory T cells in the face of the intestinal microbiota - Nature
2023年6月14日 · Recent studies have highlighted the diversity and distinct nature of regulatory T cells in the intestine, where they must balance a multitude of signals from the microbiota and …
Intestinal Regulatory T Cells - PMC
Regulatory T cells (Tregs) are critical for tuning the intestinal immune response to self- and non-self-antigens in the intestine. Its importance in intestinal homeostasis is illustrated by the onset …
Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a ...
2017年11月2日 · Intestinal intraepithelial lymphocytes (IELs) comprise one of the most abundant T cell populations and potentially provide a first line of immune defense against pathogens via …
P0088 3D tissue-level analysis of intestinal T cell dynamics reveals ...
2025年1月22日 · We developed a comprehensive volumetric imaging platform to investigate tissue-level mechanisms of colitis within the complex three-dimensional architecture of the …
Contribution of gut-derived T cells to extraintestinal autoimmune ...
2024年8月23日 · The gut microbiota can modulate the migration of intestinal T cells and enable their pathogenicity, partially through molecular mimicry. A deeper understanding of the …
Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune ...
FOXP3 + regulatory T cells (Treg cells) are a specialized population of CD4 + T cells that restrict immune activation and are essential to prevent systemic autoimmunity. In the intestine, the …