2025年1月16日 · Gram-negative bacteremia is a frequent cause of sepsis, which often must be managed prior to the receipt of microbiological data. Antibiotic treatment in the setting of sepsis in general is discussed in detail elsewhere.

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Pseudomonas aeruginosa is one of the most commonly considered gram-negative aerobic bacilli in the differential diagnosis of gram-negative infections. Consideration of this organism is important because it causes severe and often fatal hospital-acquired infections, especially in immunocompromised hosts.

Urinary tract infection (UTI): Empiric antibiotic selection for acute complicated UTI in adults; Urinary tract infection (UTI): Empiric antibiotic selection for acute simple cystitis in female adults; RELATED TOPICS. Patient education: Urinary tract infections in adults (Beyond the Basics)

2013年5月21日 · Bloodstream infection is a major cause of morbidity and mortality despite the availability of potent antimicrobial therapy and advances in supportive care. Bacteremia due to gram-negative bacilli is a significant problem in both …

2024年4月19日 · The emergence of carbapenem-hydrolyzing beta-lactamases has threatened the clinical utility of this antibiotic class and brings us a step closer to the challenge of "extreme drug resistance" in gram-negative bacilli . This topic addresses issues related to carbapenem-resistant Enterobacterales (CRE).

OBJECTIVE To evaluate the clinical efficacy of continuous versus intermittent infusion of meropenem for the treatment of ventilator-associated pneumonia (VAP) due to gram-negative bacilli.

2023年11月8日 · Among three studies evaluating inhaled colistin as adjunctive therapy to intravenous antibiotics for ventilator-associated pneumonia with drug-resistant gram-negative bacilli, predominantly A. baumannii, the pooled response rate was 80 percent .

Our data suggest that inappropriate initial antimicrobial therapy is associated with adverse outcome in antibiotic-resistant gram-negative bacteremia, particularly in patients with a high-risk source of bacteremia.

The most common clinical application (either alone or as part of combination therapy) of the aminoglycosides is for the treatment of serious infections caused by aerobic gram-negative bacilli . While less common, aminoglycosides (in combination with other agents) have also been used for the treatment of select gram-positive infections.