The nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to monoclonal antibodies. An antibody is a protein that is produced in B cells and used by the immune system of humans and other vertebrate animals to identify a specific foreign object like a bacterium or a virus .

2022年1月1日 · The new INN mAb nomenclature scheme was developed to equally divide the substances that contain an immunoglobulin variable domain into four groups: three groups for monospecific immunoglobulins and one for bispecific and multispecific immunoglobulins.

Effective December 2021, the monoclonal antibody nomenclature scheme below is being used by both the USAN Council and INN Experts to name all new monoclonal antibodies that do not already have a USAN or INN. The INN has published …

Changes to the monoclonal antibody nomenclature scheme, however, should be carefully considered and implemented only when necessary. The suffix "-mab" is used for monoclonal antibodies, antibody fragments and radiolabeled antibodies. For polyclonal mixtures of antibodies, " …

As the previous INN nomenclature scheme for monoclonal antibodies (mAb), this new INN mAb nomenclature scheme is used for all substances that contain an immunoglobulin variable domain that binds to a defined target, and that is composed of only immunoglobulin- derived pharmacologically active

2022年5月9日 · scheme for monoclonal antibodies is used for all substances that contain an immunoglobulin variable domain that binds to a defined target, and that are composed of only immunoglobulin-derived pharmacologically active components.

Antibody Nomenclature The nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to a group of medicines called monoclonal antibodies.

Revised monoclonal antibody (mAb) nomenclature scheme International Nonproprietary Names (INN) facilitate the identification of pharmaceutical substances or active pharmaceutical ingredients. Each INN is a unique name that is globally recognized and is public property.

All monoclonal antibody names end with the stem -mab. Unlike most other pharmaceuticals, monoclonal antibody nomenclature uses different preceding word parts (morphemes) depending on structure and function. These are officially called substems.

2015年8月24日 · Monoclonal antibodies are named based on a specific structure developed by the International Nonproprietary Names Working Group, under the direction of the World Health Organization. This structure consists of a prefix, substem A, substem B, and suffix.