2010年2月16日 · Exercise promotes muscle growth, whereas inactivity leads to muscle atrophy, a process that can be opposed by direct electrical stimulation. Noting that L-type Ca2+ channels …

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PIEZO1, a mechanosensitive ion channel, regulates Rho-GTPase activity and specifically accumulates at the midbody of muscle satellite cells to precisely control cell division for muscle …

2024年4月1日 · In this study, we constructed transgenic mice expressing porcine TRPC1 (Tg-pTRPC1), evaluated their growth index, muscle mass and fiber cross-sectional area, exercise …

In this study, we constructed transgenic mice expressing porcine TRPC1 (Tg-pTRPC1) to verify the effects of TRPC1 on skeletal muscle growth and elucidate the underlying mechanism. …

During development, skeletal muscle growth is thought to be largely mediated by pathways converging on the metabolic master regulator mTOR. mTOR is a serine threonine protein …

Muscle growth and differentiation are critical processes influenced by various factors, including specific proteins and signaling pathways. Recent research has focused on understanding the …

Potassium channels importantly contribute to the regulation of vascular smooth muscle (VSM) contraction and growth. They are the dominant ion conductance of the VSM cell membrane …

2013年3月21日 · Two major signaling pathways control skeletal muscle growth: the insulin-like growth factor 1– phosphoinositide-3-kinase–Akt/protein kinase B–mammalian target of …

Four correlates of muscle contraction could, in theory, regulate muscle growth: nerve-derived signals, cytoplasmic calcium dynamics, the rate of ATP consumption and physical force. Here, …