2018年4月21日 · What is the treatment for autoimmune skin diseases? The treatment of autoimmune skin diseases depends on the specific condition. Pemphigus and pemphigoid are mainly treated with systemic corticosteroids and immunosuppressive treatments [16]. Dermatitis herpetiformis is treated with dapsone and a gluten-free diet [15].

Kawasaki disease — this is an acute multisystem vasculitis with fever,and systemic and cardiac manifestations; it is the most common cause of heart disease in children; its skin signs are polymorphous exanthem (90% of which are found on the trunk and proximal limbs), perineal eruption (macular or plaque-type erythema that desquamates within ...

Skin signs include: Erythematous macules rapidly evolve into vesiculopustules and inflammatory papules. These regress over about a week. Mainly found on extremities and upper trunk; Flares every 4–6 weeks; Skin rash associated with bowel bypass syndrome

Other skin features include dry, rough skin, small vessel vasculitis, and urticarial vasculitis Sjögren syndrome is an autoimmune disease that causes dry eyes and dry mouth as it mainly affects secretory glands of the eyes and mouth.

Gluten triggers production of IgA antibodies and an autoimmune process that targets the skin and gut. In coeliac disease, gluten causes intestinal inflammation resulting in diarrhoea, tiredness, weight loss, abdominal discomfort, and metabolic consequences of malabsorption. The majority (>90%) of patients with DH also have gluten-sensitive ...

Yada N, Kudo M, Chung H, Watanabe T. Autoimmune hepatitis and immunoglobulin g4-associated autoimmune hepatitis. Dig Dis. 2013;31(5-6):415–20. PubMed; Watanabe T, Maruyama M, Ito T, et al. Clinical features of a new disease concept, IgG4-related thyroiditis. Scand J Rheumatol. 2013;42(4):325–30. PubMed; On DermNet. IgG4-related skin disease ...

Localised skin disease such as herpes zoster; Systemic viral infection, such as hepatitis C (which might modify self-antigens on the surface of basal keratinocytes) Contact allergy, such as to metal fillings in oral lichen planus (rare) and colour photographic developers; Drugs; gold, quinine, quinidine, and others can cause a lichenoid rash.

In one large family series, the skin eruption lasted 4-21 days, with a mean of 13 days. Most patients report the rash first appears before the age of 2 years. Other skin rashes described in TRAPS include: Urticaria (hive)-like plaques; Dermal oedema (deeper swelling) Generalised serpiginous (snake-like) patches and plaques

A skin biopsy may be helpful in making a diagnosis. Acute generalised blistering diseases. Acute febrile neutrophilic dermatosis . Neck, limbs, upper trunk; Pseudovesicular plaques, blisters, pustules, purpura, or ulceration; Disease associations: rheumatoid arthritis, inflammatory bowel disease, autoimmune arthritis, myeloid dysplasia; Biopsy ...

In many cases, skin rash and fever may occur intermittently for months or even years before joint pain and swelling develop. All patients with adult-onset Still disease eventually develop persistent chronic arthritis even if fever and systemic symptoms have stopped. Stiffness, swelling and pain usually affects many joints but in particular the ...