ACSL1 increased the biosynthesis of fatty acyl-CoAs including C16:0-, C18:0-, C18:1- and C18:2-CoA, triglycerides and lipid accumulation in cancer cells. Mechanistically, ACSL1 modulated …

2010年7月7日 · Long-chain acyl-CoA synthetase-1 (ACSL1) contributes 80% of total ACSL activity in adipose tissue and was believed to be essential for the synthesis of triacylglycerol.

2021年2月9日 · ACSL1 increased the biosynthesis of fatty acyl-CoAs including C16:0-, C18:0-, C18:1-, and C18:2-CoA, triglycerides and lipid accumulation in cancer cells. Mechanistically, …

2010年7月7日 · Long-chain acyl-CoA synthetase-1 (ACSL1) contributes 80% of total ACSL activity in adipose tissue and was believed to be essential for the synthesis of triacylglycerol.

2024年4月10日 · Heterologous complementation of yeast ACS mutants confirmed Tg ACS1 as being an Acyl-CoA synthetase of the bubble gum family that is most likely involved in β …

2024年2月6日 · Results: Patient sample and tissue microarray data suggested that higher ACSL1 expression is strongly associated with the malignant progression of EC. Overexpression of …

长链脂肪酰辅酶 A 合成酶 (ACSL) 是脂肪酸代谢中的一组限速酶，可催化外源或从头合成的脂肪酸生物转化为其相应的脂肪酰辅酶 A。 在这项研究中，对 ACSL 水平和脂肪酰辅酶 A 量的系统 …

2021年10月15日 · Long-chain acyl-coenzyme A synthases (ACSLs) are responsible for activating long-chain FAs and are frequently deregulated in cancers. Among the five mammalian ACSL …

Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:21242590, PubMed:22633490, …

ACSL1 increased the biosynthesis of fatty acyl-CoAs including C16:0-, C18:0-, C18:1-, and C18:2-CoA, triglycerides and lipid accumulation in cancer cells. Mechanistically, ACSL1 …