Diversity of Macrophages in Lung Homeostasis and Diseases
2021年9月23日 · In this review, we will discuss the physiological characteristics and unique functions of these three types of macrophages in acute and chronic lung diseases. We will …
Biology of lung macrophages in health and disease - Cell Press
2022年9月13日 · First, we provide a guide to identifying and distinguishing lung macrophages from other mononuclear phagocytes in humans and mice. Second, we outline emerging …
Editorial: Alveolar Macrophages in Lung Inflammation and …
Alveolar macrophages are the first line of defense against pollutants and pathogenic microbes that initiate an innate immune response in the lung. Two phenotypes of alveolar macrophages …
Macrophages in Lung Injury, Repair, and Fibrosis - PubMed
2021年2月18日 · Macrophages are activated and polarized in response to lipopolysaccharide- or bleomycin-induced lung injury. The classically activated macrophage (M1) and alternatively …
The Role of Macrophages in the Development of Acute and …
Alveolar macrophages (AMs) and interstitial macrophages (IMs) reside in the lungs. AMs are in close contact with the epithelial cells of alveoli, and IMs reside in the parenchyma between the …
Pulmonary macrophages: key players in the innate defence of
Macrophages are the most numerous immune-cells present in the lung environment under homoeostatic conditions and are ideally positioned to dictate the innate defence of the …
Biology of lung macrophages in health and disease - PubMed
2022年9月13日 · First, we provide a guide to identifying and distinguishing lung macrophages from other mononuclear phagocytes in humans and mice. Second, we outline emerging …
The impact of the lung environment on macrophage …
2022年1月11日 · Despite their key roles in lung homeostasis, macrophages are implicated in the pathogenesis of many chronic lung pathologies, including pulmonary fibrosis (PF).
Pulmonary macrophages and their different roles in health and …
2021年12月1日 · The lung resident macrophages known as Alveolar Macrophages (AM) and Interstitial Macrophages (IM) are localized in two different compartments. During lung …
The role of monocyte-derived macrophages in the lung: It’s all …
2023年6月1日 · Macrophages are present in every tissue of the body where they play crucial roles in maintaining tissue homeostasis and providing front line defence against pathogens. …
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