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In this study, we established and analyzed the chronic unpredictable mild stress (CUMS) mice to investigate the miRNA-related pathogenic mechanism involved in psychological stress-induced osteoporosis ...

Abstract: In recent years, microRNA (miRNA) has been recognized as crucial in the progression of human diseases. However, existing computational methods for identifying miRNAdisease associations often ...

Department of Clinical Laboratory, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, Suzhou 215153, China ...

The data are compelling and the study is well executed. The work is relevant to all who are interested in the biogenesis of mitochondria. Mitochondrial biogenesis requires the expression of genes ...

He is the Principal Investigator in a lab focusing on the intricate mechanisms regulating miRNA biogenesis and activity and how small RNAs shape chromatin organization. He was the recipient of the ...

The miRNAs with the highest expression levels in each study were used to identify the 10 most common miRNAs or miRNA families across studies and these were selected for subsequent target prediction.

Methodological difference and small sample sizes limit the possibility of conclusively identifying which maternal and infant characteristics affect the miRNA profile. The highly expressed miRNAs were ...

Cell type–specific miRNA effects may also be overlooked when analyzing total tissue RNA. Despite the limited mechanistic insights into the detailed functions of the 14q32 miRNAs, the study provides ...