A research team has discovered that the two key pathological hallmarks of Alzheimer's -- tau protein and beta-amyloid -- affect brain circuits in distinct yet synergistic ways, particularly those ...
Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...
They consist of aggregates of abnormally phosphorylated tau proteins that are altered in conformation. Conformational changes in tau proteins are thought to be the earliest neurobiological changes ...
A new study reveals that tau protein affects memory, while beta-amyloid disrupts emotions in Alzheimer’s disease. Using a novel mouse model, researchers found that both proteins interact to worsen ...
Tau is a microtubule-associated protein encoded by the MAPT gene located on chromosome 17q21. It promotes microtubule assembly and stability and may play a role in establishing and maintaining ...
The new research also found that tau protein in the brain, considered a hallmark of Alzheimer’s disease, may initially play a protective role against viral infections. “Identifying health ...
Tau is a microtubule-associated protein that helps to stabilize the structure of neurons, specifically by supporting microtubules, cylindrical structures that contribute to cell motility ...