Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...

For the first time, scientists have developed a drug that works on both major aggregation-promoting "hotspots" of the tau protein in the brain—a key driver of neurodegeneration. The drug ...

Working with human cells and animal models of tau-driven dementia, the researchers are the first to show that TYK2's modifications to tau contribute to tau-mediated disease. "We found that TYK2 ...

Scientists have developed two new imaging agents that work better than the only currently approved one for detecting tau ...

A comprehensive study of brain scans from more than 600 people has shed new light on the relationship between tau protein and ...

Researchers from South Korea and the United States have found a new method to eliminate the tau protein, which is known to cause Alzheimer’s disease. The research team led by Lee Jeong-soo ...

Appropriate use criteria (AUC) for the use of amyloid and tau positron emission tomography (PET) have been issued by the Alzheimer's Association and the Society for Nuclear Medicine and Molecular ...

This p-tau then suppressed ICP27, hinting that neurons may initially ramp up p-tau production to combat viral infection. Expression of herpes simplex protein ICP27 is elevated in AD brain. In infected ...