This manuscript addresses an important impediment in the field of Alzheimer's disease (AD) and tauapathy research by showing that 12 specific phosphomimetic mutations in full-length tau allow the ...
This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...
A comprehensive study of brain scans from more than 600 people has shed new light on the relationship between tau protein and amyloid-β, two central players in the progression of Alzheimer’s disease ...
Tau protein is one of these harmful proteins linked to several neurodegenerative diseases, including Alzheimer's disease, dementia, and diseases associated with head injuries, such as chronic ...
Tau protein is one such harmful protein linked to several neurodegenerative diseases, including Alzheimer's, dementia and impact-related issues like Chronic traumatic encephalopathy (CTE).
Their new research has also revealed how tau protein may initially protect the brain from the virus but later contributes to brain damage. The findings are published in Cell Reports in an article ...
Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau proteins have been found in PDD, with intermediate changes for Aβ42 in non-demented PD. The authors investigated whether AD-related ...
The study found that tau protein, typically seen as harmful in Alzheimer’s, might initially protect the brain from the virus but later exacerbate damage. HSV-1 viral proteins were observed near tau ...