Chronic traumatic encephalopathy, or CTE, is a degenerative brain disease linked to repetitive head trauma. Here's how it ...

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

Because it can only be diagnosed with an autopsy, the neurodegenerative disease is difficult to pin in cases of professional ...

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease defined by hyperphosphorylated tau (p-tau) protein accumulating in a particular pattern in specific regions of the brain.

CTE, a progressive neurodegenerative disease often linked to contact sports, has long been characterized by tau protein accumulation in the brain, and computer models have suggested that the base ...

They consist of aggregates of abnormally phosphorylated tau proteins that are altered in conformation. Conformational changes in tau proteins are thought to be the earliest neurobiological changes ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

CTE is a degenerative brain disease characterized by changes in behavior, mood and cognition, including the development of dementia. Currently it can only be diagnosed post-mortem through examination ...

He had definite CTE.” Tator said there were a number of areas in Montador’s brain where there was the presence of an abnormal protein called phosphorylated tau. The tau protein is normally ...

This manuscript addresses an important impediment in the field of Alzheimer's disease (AD) and tauapathy research by showing that 12 specific phosphomimetic mutations in full-length tau allow the ...