Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.
Methods: PBMCs from people with HIV (PWH) were treated with bryostatin-1 and tracked with proliferation dye for cell expansion. One day 6, HIV-specific CD8+ T cells were detected by tetramers staining ...
Figure 1: γ c-dependent lymphokines are required for the peripheral survival of naïve CD4 + T cells. Figure 3: Antigen-driven proliferation of CD4 + T cells is independent of γ c-cytokines.
Methods: CCK8, Colony formation, Scratch test and Transwell invasion assays were applied to determine the effects of BJO on the proliferation, migration, and invasion ability of OSCC cells in vitro.