Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell engagers (MATEs). MATEs consist of a CD3 binding domain to bind T cells and a ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

B-cells produce antibodies to attack bacteria and viruses that enter the body. T cells directly attack foreign invaders and cancer cells and produce chemicals that activate other immune cells.

ranging from intended on-target immune activation to unwanted off-target secondary responses that drive immunotoxicity and other safety considerations. In this webinar brought to you by Lonza, Ethan ...

For each time point, plates were washed in PBS, spun down, resuspended in RPMI with 10% FBS, and seeded on antibody-coated 96-well MultiScreen Filter plates (Millipore MSIPN4W50) for ASC ...

A type of treatment in which a patient`s T cells a type of immune system cell are changed in the laboratory so they will attack cancer cells. Dendritic Cell activate T cells, trigger immune responses, ...

The best T-Mobile cell phone plans give you access to unlimited data each month. But the question you need to answer when you have to pick a T-Mobile plan is which of T-Mobile's several unlimited ...

Copyright: © 2025 Elsevier Ltd. Published by Elsevier Ltd. CAR T-cell therapies have revolutionised treatment of many diseases, but their expense means many patients ...