Phenotypic features of hepatic stellate cell activation during liver injury and resolution. Following liver injury, hepatic stellate cells undergo "activation" which connotes a transition from ...

The ECM components in fibrotic liver are similar regardless of the underlying cause. Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells ...

近日，中国科学院广州生物医药与健康研究院和海军军医大学附属东方肝胆外科医院合作在Hepatology发表了题为Lhx2 specifically expressed in hepatic stellate cells promotes liver regeneration and inhibits liver fibrosis的研究论文 近日，中国科学院广州生物医药与健康研究院和海军军医 ...

Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

More information: Dmitry Victorovich Garbuzenko, Mechanisms of Epigenetic Regulation in the Fibrogenic Activation of Hepatic ...

which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during hepatitis, often resulting in liver cancer or ...