We specifically analyzed metabolic disturbances, focusing on arginine/ornithine metabolism, and assessed the potential therapeutic effects of spermine, an ornithine metabolite ... our focus lies on ...

Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of glucose and metabolites activates resident macrophages in kidneys. Resident macrophages play diverse roles on ...

Values < 0.001 are expressed as 0. Table 3. The daily amounts per 1000 kcal of polyamines in each food group. Food groups Amount Putrescine Spermidine Spermine (g/1000kcal) (µmol/1000kcal) ...

PPAR-γ is prominently expressed in activated monocytes and tissue macrophages in vivo, including the foam cells of atherosclerotic lesions 6,7. Multiple functions have been proposed for PPAR-γ ...

Putrescine significantly diminished osteoclast differentiation but did not affect purine metabolism, while spermidine promoted purine metabolism especially after TNFα stimulation, but did not affect ...

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

In the midst of countywide financial crisis, law enforcement is offering a possible solution to policing the rural communities in east county.

Request permissions for this article.

Different terms are regularly used in theories of sexuality and gender, for example sex, gender, gender identity, gender expressions, gender roles, sexual orientation. It is important to be clear ...

Copyright 2025 The Associated Press. All Rights Reserved. President Donald Trump on Monday held off on his tariff threats against Canada and Mexico for 30 days after ...

2 Department of Rheumatology and Clinical Immunology, Semmelweis University, Budapest, Hungary 4 Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary 5 Heart and ...