While durable antibody responses from long-lived plasma cell (LLPC) populations are important for protection against pathogens, LLPC may be harmful if they produce antibodies against self-proteins or ...

One form of therapy involves labeling the CD20 protein on the surface of the B cells with customized antibodies. This triggers a chain of immunological reactions and ultimately leads to the ...

Together with researchers at Newcastle University, the researchers now demonstrate how the protein IGFBP7 affects the ability of the beta cells to secrete insulin. The protein IGFBP7, which is ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

An antibody is a protein that sticks to a specific protein called an antigen. Antibodies circulate throughout the body until they find and attach to the antigen. Once attached, they can help other ...

To construct a trispecific IgG-like antibody at least three different binding moieties need to be combined, which results in a complex architecture and challenging production of these molecules. Here ...