83% of families had a genetic diagnosis of palmoplantar keratoderma (PPK). The most common genotype found in patients was AAGAB which was linked to punctate PPK. Researchers found genetic ...

Genetic analysis of palmoplantar keratoderma highlights diagnostic value and associated risks, like cardiomyopathy.

Pachyonychia congenita (PC) is a rare form of hereditary palmoplantar keratoderma (PPK) (Smith et al., 2001) and is a genetic disorder of keratinization that affects the nails, skin (particularly ...