Enrichment analysis revealed that Ang-II induced HTN causes significant metabolic shift in the brain by altering the pathways which are involved in glycolysis/gluconeogenesis (false discovery rate ...

生物节律钟在细胞内调控着一系列关键的生命进程，如细胞周期、DNA修复和能量代谢，这些过程与衰老密切相关。然而，科学界对于机体在组织损伤和修复过程中如何适应性调节核苷酸含量的机制仍知之甚少。 近日，中国药科大学生命科学与技术学院的钱民先/王中原团队在《自然-代谢》（Nature Metabolism）杂志上发表了一项重要研究，题为“The hepatic clock synergizes with ...

Figure 3 Main metabolic pathways in T cells. T cells generate ATP by glycolysis and oxidative phosphorylation. Pentose phosphate pathway (PPP) is a branch of glycolysis pathway. Cells also generate ...

Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, ...

该研究揭示了肝脏内部生物钟通过调控磷酸戊糖途径（Pentose Phosphate Pathway, PPP）来满足肝损伤修复时对核苷酸从头合成的需求。 研究人员利用代谢组 ...

Interestingly, the tumor microenvironment mostly provides factors to evade intrinsic apoptotic signaling, while glycosylation mostly regulates the extrinsic signaling pathway initiated by binding of a ...

Anna Hirsch has now taken a closer look at a less obvious difference between bacteria and humans that has not yet been pharmaceutically exploited: the so-called methylerythritol phosphate pathway ...

Department of Cardiology, The Affiliated Hospital of Qingdao University, China; Department of Urology, The Affiliated Hospital of Qingdao University, China; ...

Consecration and 10 steps to cleansing. They do dovetail with our responsibilities. What is required of a priest and how does the priesthood parallel with those who are Christians? Can you draw a ...

This cover highlights the article Structure of tetrameric forms of the serotonin-gated 5-HT3A receptor ion channel by Bianca Introini, Wenqiang Cui, Xiaofeng Chu, Horst Vogel, Shuguang Yuan, Mikhail ...