now report that the deletion of two transcription factors linked to monocyte differentiation could confer limitless self-renewal capacity to mature differentiated macrophages. Surprisingly ...

Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse ...

More information: Alexandra Blanco et al, Monocyte to macrophage differentiation and changes in cellular redox homeostasis ...

App Note / Case Study Optimized Protocol for ATCC Assay Ready THP-1 Monocyte Differentiation With PMA This protocol outlines the differentiation of ATCC Assay Ready THP-1 monocytes (ATCC® TIB-202-AR™) ...

For example, IL-4-based treatments could encourage differentiation of Ly6G + macrophages and subsequently boost progenitor cell proliferation and repair. “You have less control over that scenario, ...

Osteoclasts develop from the development of macrophages or monocytes, two types of immune cells. Suppressing osteoclast differentiation could thus be used as a therapeutic technique to prevent ...