Figure 5. Specific cell signaling related to polarization and cytokine expression of macrophages in OSCC. HMGB1 promotes M1 polarization and IL-6 secretion via TLR4/NF-κB pathway and M2 polarization ...

Hope is not passive wishing but an active, dynamic process. According to Hope Theory, hope involves two components: agency and pathways. Agency is the belief in one’s capability to act ...

In addition, macrophage polarization is regulated by two opposing pathways in arginine metabolism: The iNOS pathway, which produces citrulline and NO from arginine, induces the generation of M1 ...

"Some people may leave our platforms for virtue signaling, but I think the vast majority and many new users will find that these changes make the products better." Zuckerberg was replying to a ...

因此，寻找能够特异性抑制或重编程 M2 极化 TAMs 的靶点，有望成为一种有前景的治疗策略。 1月2日，兰州大学研究团队在期刊《Journal of Experimental & Clinical Cancer Research》上发表了研究论文，题为“Gastric cancer-derived exosomal let-7 g-5p mediated by SERPINE1 promotes ...