Citation: Macrophages, not T cells, may hold key to predicting which melanoma patients are more likely to respond to immunotherapy (2025, January 8) retrieved 17 January 2025 from https ...

Hence, pathways that regulate macrophage phenotype are of strategic interest, with reprogramming strategies focusing on inhibitors of phosphoinositide 3-kinase-gamma (PI3Kγ) due to restricted immune ...

Obesity is associated with chronic, low-grade inflammation. Excessive nutrient intake causes adipose tissue expansion, which may in turn cause cellular stress that triggers infiltration of ...

Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

The study was published in the journal JCI Insight. Macrophages are immune cells that reside in and protect the lungs and are also recruited to the lungs in high numbers during injury or disease.

Macrophages, key modulators of immune responses, play a dual role in both promoting and resolving inflammation. Exosomes, small extracellular vesicles released by various cells, carry bioactive ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

An interview on how advanced techniques can be used to enhance silk fibroin and chitosan for drug delivery applications.

They showed that symbioses with bacteria have ... Microbial Cell Factories May Help Get to the Root of Understudied Plant Molecules Jan. 16, 2025 — A new tool could make it easier to study ...