Objectives The circadian clocks are internal timing mechanisms that drive ∼24-hour rhythms in a tissue-specific manner. Many aspects of the physiology of the intervertebral disc (IVD) show clear ...

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A broad-based horizontal morphology with adjacent degenerative features (intervertebral disc degeneration and/or end plate changes) were deemed to be a degenerative osteophyte. A thorn-like angulated ...

Therefore, automating the patient-specific modeling process is essential. Methods: We developed an automated and robust pipeline that generates and simulates biofidelic vertebrae and intervertebral ...

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PS: The paper trains the model for 100 epochs for a fair comparison. You can use more data and train for more epochs to get better performance.

Two well-calibrated readers (FdB, MOT) assessed all MRIs and radiographs for degenerative lesions. Adjudication was performed (MR for MRI and AF for radiographs) on a per-lesion basis, except for the ...

The pain in patients with Modic type 1 changes (MC1) is often due to vertebral body endplate pain, which is linked to abnormal neurite outgrowth in the vertebral body and adjacent endplate. The aim of ...