In this manuscript, Hoon Cho et al. presents a novel investigation into the role of PexRAP, an intermediary in ether lipid biosynthesis, in B cell function, particularly during the Germinal Center (GC ...

This study provides useful insights into the ways in which germinal center B cell metabolism, particularly lipid metabolism, affects cellular responses. The authors use sophisticated mouse models to ...

School of Mathematical and Physical Sciences, University of Technology Sydney, Ultimo, New South Wales 2007, Australia ARC Centre of Excellence for Transformative Meta-Optical Systems, University of ...

Additionally, the GC acts as a signalling hub to regulate a multitude of cellular processes, including cell polarity, motility, apoptosis, DNA repair and cell division. In light of these crucial roles ...

a team of researchers from the Center for Neural Science at New York University (NYU) published a paper in Nature Communications showing that nerve tissue and kidney tissue cells also store a kind ...

Abu Dhabi: In a groundbreaking advancement toward cell therapy and regenerative medicine, the Abu Dhabi Stem Cells Center (ADSCC) has successfully developed clinical-grade induced pluripotent stem ...

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Strong support for targeting B cells is provided by genetic, immunological and clinical observations that place these cells at the center of SLE pathogenesis, as initiating, amplifying and ...

What’s behind the building’s name? Imaging is a central element in our field of research which we use systematically to analyse cellular processes in organisms. Using a variety of imaging technologies ...