(Top left) Immunosuppressive TME: the CRC microenvironment is rich in immunosuppressive cells, such as TAMs, Tregs, and MDSCs, which inhibit CAR-T cell function. (Top middle) Tumor heterogeneity: CRC ...

The study identified gene expression changes which were detected beginning three months after intranasal dosing of foralumab in our ongoing ISPPEA (or expanded access program). Key findings include ...

调节性T细胞是维持机体免疫稳态的CD4+ T细胞亚群，也是肿瘤微环境中免疫抑制屏障的主要构成细胞。因此，特异性地调控肿瘤微环境的Treg细胞使其功能与稳定性发生改变，将能够促进肿瘤杀伤反应的发生。

Copyright: © 2025 Elsevier Ltd. Published by Elsevier Ltd. CAR T-cell therapies have revolutionised treatment of many diseases, but their expense means many patients ...

2Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo, Japan. 6Department of Immunogenomic Medicine, Research ...

--(BUSINESS WIRE)--Atara Biotherapeutics, Inc. (Nasdaq: ATRA), a leader in T-cell immunotherapy, leveraging its novel allogeneic Epstein-Barr virus (EBV) T-cell platform to develop transformative ...

Consultation on a discussion document about the Regulatory Standards Bill (RSB) has been gaining increasing public interest in the wake of the Treaty Principles Bill. The Ministry of Regulation ...

T-Mobile is one of the fastest-growing carriers in the United States thanks to aggressive pricing, marketing, and a penchant for doing the unexpected. The Uncarrier has significantly shaken up the ...

The Regulatory Standards Bill is "dangerous" and "alarm bells need to ring", critics of the proposed government legislation say. Feedback on proposals that will inform the Regulatory Standards Bill ...

Nigerian banks posted bumper profits in 2024 against the backdrop of a fresh recapitalisation exercise and regulatory shocks such as board/management dissolutions and license revocations, writes ...

The best T-Mobile cell phone plans give you access to unlimited data each month. But the question you need to answer when you have to pick a T-Mobile plan is which of T-Mobile's several unlimited ...