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as exemplified by the opposite outcomes that can arise from the interaction of MSCs with DCs and NK cells in the presence of high or low concentrations of IFNγ. A final issue of crucial ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

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while the more recently established mouse lines still require high levels of activated NOTCH1 for maintenance of their tumor phenotype. Aberrant NOTCH1 signaling in CUTLL1 cells is dependent on γ ...