The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...

In a nutshell Scientists discovered that random DNA mutations don’t just cause local damage, they trigger widespread changes ...

DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views ...

Researchers at University of California San Diego School of Medicine have published results that shed new light on an old ...

The study employed high-throughput methods such as barcoded bisulfite amplicon sequencing to measure methylation at androgen-sensitive cytosine-phosphate-guanine (CpG) sites, specifically ...

3 for use in foods and ingested drugs based on results from animal studies and a legal technicality, teeing up reformulations for numerous CPG products ... eugenol methyl ether (methyl eugenol ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

Introduction: DNA methylation inhibitors have been approved for the prevention of Acute Myeloid Leukemia (AML), and their safety profile is not fully characterized. This study was aimed at evaluating ...

College of Animal Science and Technology, Southwest University, Chongqing 400715, China College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China ...