Again, these results were confirmed by inhibiting autophagy with RNA interference instead of chloroquine. Additional treatment with chloroquine had no further benefit in this setting. This study ...

In chloroquine induced autophagy the surface charge of the outer plasma membrane changes which F2N12S can measure by alterations in the intensity of the two emissions, which emit more at 530nm (green) ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

In general, this is not an early event in autophagy and the the role of PS externalization is unclear in autophagy ... as a marker for autophagosomes and hence the detection of autophagic cells. The ...