Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77845, United States ...

126 Azurophilic granules (primary) are the first to form and contain myeloperoxidase, cathepsin G, and defensin to destroy microorganisms. These are followed by the formation of specific granules ...

Cell Lysate Cathepsin B (CTSB) Activity Assay Cell lysates were produced as described above. 2 μl of the cell lysates were incubated with 20 μM fluorogenic CTSB substrate (Z-RR-AMC; Enzo; ...

Here we proposed to evaluate the importance of Cathepsin B on NLRP3 inflammasome assembly and activation. Using Cathepsin B –/– BMDMs (Bone Marrow-Derived Macrophages), we first show that Cathepsin B ...