Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

The gut microbiome, or the community of microorganisms residing in the gastrointestinal tract, has emerged as an important ...

Similar to humans, plants have an immune system to help defend against parasites and other deleterious infections. The human body is interconnected with ce | Immunology ...

There are two big buzzwords in beauty these days: inflammaging and reverse aging.

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...

Radiotherapy is a cornerstone of cancer care. However, in recent decades, Sweden has fallen behind in this area, both in ...

Many cancers upregulate an amino acid transporter to fuel their growth, making this protein a promising tool in tumor ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and deadly forms of cancer. This means it grows and ...

B lood is made up of red blood cells, white blood cells, platelets, and plasma. Markers called antigens are found on the ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...