Venetoclax (Brand name: Venclexta) is a targeted treatment for chronic lymphocytic leukemia (CLL). It targets a specific protein called BCL-2 in cancer cells that helps them stay alive. Doctors ...

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We are also accelerating research to confront the growing burden of COVID-19, HIV and cancer-related infectious diseases worldwide. BBE's nearly 34 faculty members model epidemics, research ...

Chronic lymphocytic leukemia (CLL) is a cancer of a white blood cell group called a B lymphocytes. It starts in the bone marrow tissue where these B cells are formed. While doctors aren't exactly sure ...

SNV is under clinical development by Calidi Biotherapeutics and currently in Phase I for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia). According to GlobalData, Phase I drugs for Acute ...

Myeloproliferative neoplasms are blood cancers that affect myeloid stem cells. Treatment can involve targeted medications or careful monitoring. Myeloproliferative disorders are a group of cancers ...

Kymera Therapeutics, Inc., 500 North Beacon Street, Watertown, Massachusetts. *Corresponding Author: Yogesh K. Chutake, Kymera Therapeutics, Inc., 500 North Beacon ...

These cancers include esophageal carcinoma (ESCA), gastric cancer (GC), glioma, laryngeal squamous cell carcinoma (LSCC), acute myeloid leukemia (AML), lung adenocarcinoma (LUAD), nasopharyngeal ...

Instead, the researchers used a leukemia mouse model with a defective genetic proofreading system called Polg, which gradually accrues mtDNA mutations. By disrupting Polg's proofreading function ...

Introduction: Progressing myelodysplastic syndrome (MDS) into acute myeloid leukemia (AML) is an indication for hypomethylating therapy (HMA, 5-Azacytidine (AZA)) and a BCL2 inhibitor (Venetoclax, VEN ...