Plasma cells (PCs) are the terminal differentiation stage of activated B cells and serve as crucial effector cells in humoral immunity. While PCs have ...

You will be redirected to our submission process. B lymphocytes, identified more than half a century ago, are crucial for sustained host immune responses to pathogens through differentiation into long ...

The aim of this project is to understand the structure and function of epigenome loops for cell differentiation.We will focus on the differentiation of plasma cells, which produce antibody, as a model ...

Ectopic expression of this plasma cell signature-miRNA in primary mouse B cells accelerated the differentiation into antibody-secreting plasmablast, as indicated by upregulation of CD138 and enhanced ...

In striking contrast to the conventional plasma membrane FcRs, FCRLA binds multiple isotypes of Ig ... One of the major research projects in the Hu laboratory is to study Tfh cell differentiation and ...

Background and Objectives Long-lived plasma cells (LLPC) contribute significantly to the production of ... LLPC has to be connected with the prevention of regeneration of these cells through the ...

Cell Culture Substrates,Stem Cells,Surface Chemistry,Surface Topography,Allylamine,Amino Acid Backbone,Bioactive Signaling,Cell Adhesion,Cell Attachment,Cell Culture ...

She is especially experienced on the research of mesenchymal stem cells, including isolation, characterization, and differentiation. She has published around 20 peer-reviewed articles in prestigious ...

The goal of the James Lab is to learn how human B cells differentiate into long-lived antibody-secreting plasma cells. We would like to better understand how dysregulated B cell differentiation can ...

Their findings were recently published in the journal Cell Death & Differentiation. When the lipids in the plasma are ...