The company’s multi-tumor associated antigen (multiTAA) technology, originally developed at the Baylor College of Medicine in Houston, Texas, USA, is based on the selective expansion of a broad ...

Once in the tumor, CAR-M are activated by tumor-associated antigen engagement with the CAR, signaling via CD3-ζ to phagocytose the tumor cell and release cytokines and chemokines that ‘warm up ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

From published reports, a prioritized list ranking 75 tumor-associated vaccine antigens by these criteria is presented. Given the large number of potential tumor vaccine antigens, and the general ...

China Emerging Key Player in Development Of Gamma Delta T Cell Cancer Therapy Says KUICK RESEARCHDelhi, Jan. 29, 2025 (GLOBE ...

C.M. Laumont et al., “Noncoding regions are the main source of targetable tumor-specific antigens,” Sci Transl Med, 10:eaau5516, 2019. In pursuit of safe and effective cancer therapies, researchers ...

What is TP53 and what role does it play in cancer? Medically reviewed by Marla Anderson, MD. The TP53 gene is a gene that is ...

Receptors on the surface of cytotoxic T cells recognize peptides presented by major histocompatibility complex (MHC) molecules on the tumor cell membrane. CD8 acts as a T-cell co-receptor that ...

Studies on clear renal cell carcinoma have found a link between immunotherapy response and HERV signatures, indicating that ...

AUSTIN, TX, USA and HAMILTON, Canada and SAN DIEGO, CA, USA I7, 2025 I Triumvira Immunologics, a clinical-stage company ...

We were also the first to report that tumor growth induces monocyte-derived tumor-associated macrophages (TAMs ... Moreover, we found that monocyte-derived TAMs function as antigen-presenting cells to ...