This review provides a summary of the suppressive mechanisms used by Tregs and highlights seminal work linking intestinal inflammation with loss of Treg function in both animal models of disease and ...
to investigate whether the generation of inducible Foxp3-expressing regulatory T cells (Treg) might constitute additional mechanisms underlying the immunosuppressive properties of MMF. The animals ...
On the other hand, Tregs mediate immunological tolerance against self-antigens and harmless foreign antigens such as food and intestinal microbiota. Furthermore, they control the immune response via ...
Of these, transcoelomic metastasis is the most common, and is responsible for the greatest morbidity and mortality in women with this disease. Unfortunately, very little is known about the mechanisms ...
These experiments reveal a key underlying mechanism for the loss of immune regulation in MS and likely other autoimmune diseases. They also add mechanistic insight into how Treg [regulatory T ...
The human immune system is a complex network of cells and signals that guards against disease, yet in the case of cancer, it often struggles to mount an effective response. Recent research, published ...