Tau is a microtubule-associated protein that helps to stabilize the structure of neurons, specifically by supporting ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.

Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to ...