Chronic traumatic encephalopathy, or CTE, is a degenerative brain disease linked to repetitive head trauma. Here's how it affects the brain and who is most at risk.

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease defined by hyperphosphorylated tau (p-tau) protein accumulating in a particular pattern in specific regions of the brain.

Repetitive head impacts appear to be the chief risk factor for CTE, which is characterized by misfolded tau protein that is unlike changes observed from aging, Alzheimer’s disease, or any other ...

A research team has discovered that the two key pathological hallmarks of Alzheimer's -- tau protein and beta-amyloid -- affect brain circuits in distinct yet synergistic ways, particularly those ...

Because it can only be diagnosed with an autopsy, the neurodegenerative disease is difficult to pin in cases of professional ...

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

He had definite CTE.” Tator said there were a number of areas in Montador’s brain where there was the presence of an abnormal protein called phosphorylated tau. The tau protein is normally ...

They consist of aggregates of abnormally phosphorylated tau proteins that are altered in conformation. Conformational changes in tau proteins are thought to be the earliest neurobiological changes ...

CTE is a degenerative brain disease characterized by changes in behavior, mood and cognition, including the development of dementia. Currently it can only be diagnosed post-mortem through examination ...

Still, the team notes “a human specimen with the same tau pathology present in the male bighorn sheep would have likely been diagnosed with mild CTE.” Taken together ... The report failed to prove ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's—tau protein and beta-amyloid ...