The field of immunology has long recognized the pivotal role of T lymphocytes in the adaptive immune system, particularly in pathogen defense, tumor ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...

Researchers have uncovered why some vaccines last longer than others. A study reveals that megakaryocytes, blood cells involved in clotting, play a crucial role in vaccine durability.

The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance. In order to propagate malignancy, circRNAs shuttle ...

Briefly, SYT-SSX-specific T-cells were expanded via two-step fast stimulation protocol as described before, and Pep-4-specific T-cell activation was determined by IFN-γ production and target cell ...

USA dDepartment of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA eDepartment of Pathology, Albert Einstein College of Medicine, 1300 Morris Park Ave, ...

One such voice is author and therapist Amanda Gregory. She asserts that while forgiveness is helpful for some, it isn't necessary for everyone — especially trauma victims like herself.

The basophil activation test (BAT) is an in vitro assay, in which activation of an individual's own basophils is quantified ... It is also debatable whether the use of basophils is suitable for the ...