Recent evidence indicates that, despite similarities in molecular and gene expression profiles between analogous neurons in the human and rodent neocortex, ...
Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.
A research team led by Shujia Zhu from the Chinese Academy of Sciences’ (CAS) Center for Excellence in Brain Science and Intelligence Technology and Yang Li from the Shanghai Institute of Materia ...
Subsequently, the conductivity and carrier transmission efficiency of the device were effectively improved by organic ... the device can achieve low-voltage operation and typical synaptic functions ...
We find distinct synaptic signatures of L5 IT and PT neurons that are defined by proteins regulating synaptic organization and transmission, including cell-surface proteins (CSPs), neurotransmitter ...
Working with proteomics expert Prof. Andy Howden (University of Dundee, UK), they discovered that while both types of neurons share some synaptic proteins, they also have unique features that may ...
In all of the experiments described below, glutamatergic and GABAergic synaptic transmission was blocked pharmacologically, and leak and capacitive currents were subtracted offline. Except where ...