Phenotypic features of hepatic stellate cell activation during liver injury and resolution. Following liver injury, hepatic stellate cells undergo "activation" which connotes a transition from ...

The cellular localization of AURKA was determined through double immunofluorescence staining in human fibrotic liver tissues and primary mouse hepatic stellate cells. RNA interference and AURKA ...

The paradigm of stellate cell activation provides an important framework ... hepatic fibrosis is to clear the primary cause of liver disease. The latter includes abstinence in the case of ...

Furthermore, QZRG granules inhibited the expression of apoptosis-related proteins BAX, Caspase9, Caspase8, and Caspase3, while reducing P2Y14 expression in fibrotic liver tissues. Additionally, QZRG ...

Design Levels of BMP-9 and its receptors were analysed in primary liver cells. Direct effects of BMP-9 on hepatic stellate cells (HSCs) and hepatocytes were studied in vitro, and the role of BMP-9 was ...

Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

14 Southern California Research Center for ALPD and Cirrhosis, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA The field of pancreatic stellate cell (PSC ...

近日，中国科学院广州生物医药与健康研究院和海军军医大学附属东方肝胆外科医院合作在Hepatology发表了题为Lhx2 specifically expressed in hepatic stellate cells promotes liver regeneration and inhibits liver fibrosis的研究论文 近日，中国科学院广州生物医药与健康研究院和海军军医 ...

This suggests these cells may be useful as new therapeutic targets for various liver conditions. The work appears in the journal Immunity. Macrophages are specialized immune cells located in every ...

People with cirrhosis are at an increased risk of liver cancer. Treatment may include surgery, a liver transplant, ablation therapy (a needle or probe is used to kill cancer cells), embolization ...