Cassava's strong liquidity with $128.6 million in cash supports early-stage development, yet long-term funding needs may lead ...

Activated AKT regulates the TSC1-TSC2 complex, which controls Rheb GTPase, thereby activating mTORC1. mTORC1 promotes protein synthesis (via 4E-BP1 and S6K), lipid biogenesis (via SREBP1 and PPARγ), ...

Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg 405 30, Sweden ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Gene-engineered immune cell therapies have partially transformed cancer treatment, as exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic malignancies. However, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Internal translation initiation sites, as ...