Most antihypertensive drugs target the renin-angiotensin system and fall in two drug classes: angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs). ACE cleaves a ...

Drugs that interfere with the renin–angiotensin system can provide renoprotection in patients with diabetic nephropathy, possibly by exerting an antiproteinuric effect. Aldosterone might have a ...

The validity as well as the usefulness of measuring components of the renin-angiotensin-aldosterone system in the diagnosis and treatment of patients with elevated blood pressure (BP) has been ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

This prospective case-control study included 85 patients with lung involvement related to the COVID-19 virus and a group of ...

was looking at gene expression data from the lung fluid of COVID-19 patients on his computer screen when he spotted something striking—the expression of genes for key enzymes in the renin-angiotensin ...

Research explores the role of the brain’s (pro)renin receptor (PRR) and other members of the renin angiotensin system in the development of hypertension, metabolic syndrome, and heart failure.

The two primary mechanisms — considered “neurohormonal” responses — are activation of the sympathetic nervous system (SNS) and activation of the renin-angiotensin-aldosterone system (RAAS).

Lisinopril inhibits angiotensin-converting enzyme. It suppresses the renin-angiotensin-aldosterone system. The mechanism of the antihypertensive effect of thiazides is unknown. Fetal toxicity may ...