This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...

We have optimized a cost-effective, medium-throughput, fluorescence intensity-based protease activity assay specifically for aboveground plant tissue that balances precision and throughput, the latter ...

Shionogi will receive $375 million to develop a long-acting protease inhibitor designed to prevent SARS-CoV-2 infection in people who are immune compromised.

This study presents a valuable finding on the role of secretory leukocyte protease inhibitors (SLPI) in developing Lyme disease in mice infected with Borrelia burgdorferi. The evidence supporting the ...

[13] HIV genotypic assays detect specific mutations or nucleotide substitutions in the gag-pol region of the HIV-1 genome. This region encodes for the reverse transcriptase and protease enzymes ...

Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Lahore 54570, Pakistan ...

Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China ...

Among the identified putative protease inhibitors, a series of broad-acting compounds targeting the coronavirus 3CL protease and papain-like protease were validated through biochemical and live virus ...

NA activity was determined in 96-well white U-bottom microplates (Greiner bio-one GmbH, Frickenhausen, Germany) using the CL-based NA-Star assay (NA-Star Influenza Neuraminidase Inhibitor ...