This study presents a valuable finding on the role of secretory leukocyte protease inhibitors (SLPI) in developing Lyme disease in mice infected with Borrelia burgdorferi. The evidence supporting the ...

We have optimized a cost-effective, medium-throughput, fluorescence intensity-based protease activity assay specifically for aboveground plant tissue that balances precision and throughput, the latter ...

Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas 77845, United States ...

Department of Chemical Biology, Helmholtz Centre for Infection Research, Inhoffenstr. 7, Braunschweig 38124, Germany German Center for Infection Research (DZIF), Hannover-Braunschweig Site, ...

Shionogi will receive $375 million to develop a long-acting protease inhibitor designed to prevent SARS-CoV-2 infection in ...

Proteolytic enzymes are integral to various cellular functions, including extracellular matrix (ECM) remodeling, digestion, and immune modulation. These ...

Cytonics Corporation, a private biotechnology company developing cutting-edge biologic therapies for musculoskeletal conditions, today announced that the first nine patients in its Phase 1 clinical ...

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...

Then, in 1985, Abbott launched the world's first HIV antibody assay. In 1996, one of the first protease inhibitor drugs indicated in combination with other antiretroviral agents for the treatment ...

NA activity was determined in 96-well white U-bottom microplates (Greiner bio-one GmbH, Frickenhausen, Germany) using the CL-based NA-Star assay (NA-Star Influenza Neuraminidase Inhibitor ...

highlighting cyclin-dependent kinase inhibitors as potential novel therapeutic agents. Acute respiratory distress syndrome (ARDS) is a neutrophil-dominant disease with significant morbidity and ...