1Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany. *Corresponding Author: Maximilian Merz, Department of Hematology, Hemostaseology and ...
Research on human pre-B cells indicates that the majority of antibodies expressed by early immature B cells exhibit self-reactivity. A total of 55%–75% of newly generated B cells in the bone marrow ...
This differentiation process can be seen as a kind of biological specialization course, which ends when they become cells that secrete antibodies specific to the pathogen or become memory cells.
In this section, we will discuss how these cells interact with DCs under various microenvironments. Interaction of DCs with epithelial cells secretes ... differentiate into plasma cells to release ...
Treatment of tumor cells with neuraminidases or a sialyl transferase inhibitor significantly reduced binding of a soluble recombinant Siglec-9-Fc fusion protein, while EGFR and HER2 expression ...