While durable antibody responses from long-lived plasma cell (LLPC ... CD28 is a co-stimulatory molecule best known for its role in T cell activation. In LLPC, CD28 has been suggested to contribute to ...

Laboratory tests showed anemia (Hb: 6.7 g/dL; hematocrit: 21%) and cholestasis (total bilirubin: 16.01 mg/dL; direct bilirubin ... an uncommon but severe complication of sickle cell disease. Efforts ...

Her total bilirubin and lactate dehydrogenase concentrations ... the patient recalled being told that she had sickle cell trait, but denied ever having a sickle cell crisis. Laboratory tests ...

Overall, the life expectancy of patients with SCD is lower than that of persons without SCD. 1 However, life expectancy varies depending on the type of disease, treatments administered, and ...

Smooth muscle cells (SMCs) of the proximal thoracic aorta are derived from second heart field (SHF) and cardiac neural crest (CNC) lineages. Recent studies, both in vitro and in vivo, have implied ...

The diagnosis of hemolytic anemia was confirmed: the half-life of Cr 51-tagged red cells was 14 days (normal ... ranged from 5 to 8 per cent; plasma bilirubin, predominantly indirect, was 1.5 ...

The Peyer's patches contained dense Iba1-ir cells and vascular structures, i.e., arterioles, venules, capillaries, and lymphatic draining (Figure 13H) in all segments. The vascular distribution ...

Scientists have created baby mice with two fathers for the first time by turning male mouse stem cells into female cells in a lab. This raises the distant possibility of doing the same for people ...

Bahrain hopes to become the first Arab country to manufacture plasma as a sickle cell society plans to pursue the proposal with the government this year. The nation has sufficient quantity of ...

In blood vessels, bilirubin attenuates cholesterol deposition and immune cell infiltration to decrease plaque formation. In the liver, bilirubin and BVRA (biliverdin reductase A) phosphorylates AKT ...