[14] Pegylated interferon alfa is a pregnancy category C medication. Standard interferon alfa-2b has also been shown to have abortifacient effects in experimental animals. Use of either product is ...

Background and Aim: Current practice guidelines recommend that individuals chronically infected with the hepatitis C virus (HCV) be treated with pegylated interferon plus ribavirin. Ribavirin ...

Department of Hepatobiliary and Pancreatic Medicine, The First Hospital of Jilin University Changchun, Changchun, Jilin, China Background: Sequential or combined treatment with nucleos(t)ide analogs ...

Department of Biological Science and Technology, Center for Intelligent Drug Systems and Smart Bio-devices (IDS 2 B), National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan Department of ...

Introduction: The minority of the chronic hepatitis B (CHB) patients received polyethylene glycol interferon (PEG-IFN) combined with nucleotide analogs (NAs) can obtain hepatitis B surface antigen ...

GSK is conducting trials of bepirovirsen with other therapeutics, with the aim of increasing functional cure rates, including a phase 2b trial in combination with pegylated interferon and a phase ...

Treatment with xalnesiran, a small interfering RNA molecule, plus an immunomodulator resulted in hepatitis B surface antigen loss among adults with chronic HBV infection, according to a study ...

Usually, you have to take them for a few weeks.Patients can be given ribavirin (a pill or capsule) and pegylated interferon (a weekly injection). Another alternative is taking daclatasvir and ...

The drug candidate is a pegylated human interferon lambda 1- lambda 3 chimeric protein, that acts by targeting interferon lambda receptor 1 (IL28RA or IFNLR1). It is developed based on Prositsole ...

In addition, nanotechnology has contributed to a wide variety of anti-infective products, from pegylated interferons, used in viral disease, to nanocrystalline silver, used topically in wound ...

So far, licensed treatments include extended-effect interferon, pegylated interferon (IFN), ribvirin (RBV), protease inhibitors such as boceprevir, telaprevir, simeprevir, and sofosbuvir and ...